Antioxidant and Anti-Elastase Activity of Ethanol Extract of Tomato (Solanum lycopersicum L.)

Alhoi Hendry Henderson, I Nyoman Ehrich Lister, Edy Fachrial, Ermi Girsang


Skin aging due to the damage caused by ultraviolet radiation and toxic ingredients in cosmetics is still a problem. Tomato has antioxidant and skin protection activities. The study aimed to investigate the potential of tomato as an antioxidant and elastase inhibitor. A 170 g of tomato simplicial powder was extracted using ethanol 70% by the maceration method. Antioxidant activity was measured through 2,2’-Azino-bis 3-ethyl benzothiazoline-6-sulphonic acid (ABTS)-reducing activity. The antiaging activity was measured through anti-elastase activity. Tomato extract (SLE) showed strong ABTS-reducing activity (IC50 = 86.66 ± 10.58) and very strong anti-elastase activity (IC50 = 19.73 ± 0.44). In conclusion, there was a linear correlation between antioxidant activity and anti-elastase activity. However, the antioxidant activity and anti-elastase activity of tomatoes were still below lycopene (IC50 antioxidant = 49.23 ± 2.06 µ and IC50 anti-elastase = 10.39 ± 0.43 49.23 ± 2.06 µ However, it was worth to be developed as a natural product as an antioxidant and anti-elastase.  Further study is required to do fractionation to get the purer lycopene compound from tomato.


Solanum lycopersicum; ABTS; lycopene; herbals; skin aging

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