Potensi Nephrolepis spp. sebagai Tanaman Obat Koleksi Kebun Raya Purwodadi Berdasarkan Kajian Etnomedisin dan Fitokimia

Elga Renjana, Muhamad Nikmatullah, Elok Rifqi Firdiana, Linda Wige Ningrum, Melisnawati H. Angio

Abstract


Tumbuhan telah dikenal sebagai sumber obat alami yang dapat menyembuhkan berbagai macam penyakit karena mengandung senyawa metabolit sekunder dengan aktivitas biomedik. Tumbuhan paku merupakan kelompok tumbuhan tertua di bumi yang memiliki lebih dari 12.000 jenis. Tumbuhan paku mengandung senyawa metabolit sekunder yang berpotensi obat berdasarkan
studi etnobotani dan farmakologi. Sebanyak 20 suku dan 38 marga tumbuhan paku dikoleksi dan dikonservasi secara ex situ oleh Kebun Raya (KR) Purwodadi. Nephrolepis merupakan salah satu marga dari koleksi tumbuhan paku KR Purwodadi dengan jumlah spesimen paling banyak. Nephrolepis termasuk kelompok tumbuhan paku epifit atau setengah epifit yang daunnya tersusun
menyirip tunggal seperti pedang. Selama ini Nephrolepis hanya dikenal sebagai bahan sayuran dan tanaman hias oleh masyarakat. Namun belum ada informasi mengenai potensi obat dari koleksi Nephrolepis tersebut. Oleh karena itu, penelitian ini dilakukan untuk menginventarisasi dan mengarakterisasi potensi koleksi Nephrolepis di KR Purwodadi sebagai tanaman obat. Metode yang
digunakan pada penelitian ini adalah inventarisasi data dari Sistem Informasi Katalog Koleksi Tanaman (SIKATAN), pengamatan langsung di rumah kaca, dan studi etnomedisin dan fitokimia berdasarkan literatur. Berdasarkan hasil inventarisasi, telah diperoleh 36 spesimen yang termasuk dalam 6 jenis Nephrolepis. Spesimen tersebut memiliki potensi mengobati berbagai macam penyakit, baik yang telah dikenal dalam pengobatan tradisional maupun dari hasil penelitian. Koleksi Nephrolepis tersebut mengandung berbagai senyawa, seperti alkaloid, flavonoid, dan terpenoid yang memiliki aktivitas farmakologi, di antaranya antioksidan, antiinflamasi, antimikroba, antivirus, dan antikanker. Di samping itu, jenis N. cordifolia merupakan koleksi yang paling potensial
sebagai obat karena bagian daun, rimpang, hingga umbinya memiliki aktivitas antiinflamasi, antimikroba, antikanker, antimalaria, dan antioksidan.


Keywords


Etnomedisin; fitokimia; tumbuhan paku Nephrolepis

Full Text:

PDF

References


Adebiyi, A.O., Oyeyemi, S.D., Tedela, P.O. & Ojo, V.I. (2019) GC-MS analysis of bioactive compounds from n-hexane leaf extract of a tropical fern, Nephrolepis cordifolia (L) C. Presl. East African

Scholars Journal Biotechnology and Genetics, 1 (5), 118–123. doi:

36349/EASJBG.2019.v01i05.004.

Appiah, K.S., Oppong, C.P., Mardani, H.K., Omari, R.A., Kpabitey, S., Amoatey, C.A., Onwona-Agyeman, S., Oikawa, Y., Katsura, K. & Fujii, Y.

(2018) Medicinal plants used in the Ejisu-Juaben Municipality, Southern Ghana: An ethnobotanical study. Medicines (Basel), 6 (1), 1. doi: 10.3390/medicines6010001.

Azkiyah, S.Z. (2013) Isolasi senyawa aktif antioksidan dari fraksi n-heksana tumbuhan paku Nephrolepis falcata (Cav.) C. Chr. Skripsi S1. UIN Syarif Hidayatullah.

Baskaran, X.R., Vigila, A.V.G., Zhang, S.Z., Feng, S.X. & Liao, W.B. (2018) A Review of the use of pteridophytes for treating human ailments. Journal of Zhejiang University-SCIENCE B, 19 (2), 85–119.

doi:10.1631/jzus.B1600344.

Bassey, M.E., Johnny, I.I., Umoh, O.T. & Douglas, F.T. (2020) Phytomedicinal potentials of species of Nephrolepis (Schott.). World Journal of Pharmaceutical Research, 9 (4), 1400–1410. doi:

20959/wjpr20204-17133.

Cambie, R.C. & Ash, J. (1994) Fijian medicinal plants. Australia, CSIRO.

Chang, H.C., Gupta, S.K. & Tasay, H.S. (2011) Studies on folk medicinal fern: An example of “Gu Sui-Bu”. In: Fernandez H., Kumar A. & Revilla, M.A. (eds.) Working with Ferns, Issues, and Applications.

London, Springer, pp. 285–304.

Chen, I.N., Chang, C.C., Ng, C.C., Wang, C.Y., Shyu, Y.T. & Chang, T.L. (2008) Antioxidant and antimicrobial activity of Zingiberaceae plants in Taiwan. Plant Foods for Human Nutrition, 63 (1), 15–20. doi:10.1007/s11130-007-0063-7.

Chung, K.T., Wong, T.Y., Wei, C.I., Huang, Y.W. & Linn, Y. (1998) Tannins and human health: A review. Food Science and Nutrition, 38 (6), 421–464. doi:10.1080/10408699891274273.

Darnaedi, D. & Praptosuwiryo, T.N. (2016) Nephrolepis (PROSEA). [Online] Tersedia pada: https://uses. plantnet-project.org/en/Nephrolepis_(PROSEA) [Diakses 10 Juni 2020].

Daval, N. (2009). Consevation and cultivation of ethnomedicinal plants in Jharkhand. In: Trivedi, P.C. (ed.) Medicinal Plants Utilisation and Conservation. Jaipur, Aavishkar Publishers Distributor, pp. 130-136.

Dayanti, R. & Suyatno (2012) Aktivitas antioksidan ekstrak metanol bagian batang tumbuhan paku Nephrolepis radicans (Burm.) Kuhn. UNESA Journal of Chemistry, 1 (1), 86–92.

El-Tantawy, M.E., Afifi, M.S. & Shams, M.M. (2015) Chemical composition, antimicrobial and cytotoxic activities of volatile constituents from the subterranean organs of Nephrolepis cordifolia (L.) C. Presl and Nephrolepis exaltata (L.) family Nephrolepidaceae grown in Egypt. Canadian Journal of Pure and Applied Sciences, 9 (2), 3365–3370.

Govindappa, M., Naga, S.S., Poojashri, M.N., Sadananda, T.S., Chandrappa, C.P., Santoyo, G., Sharanappa, P. & Kumar, A.N.V. (2011) Antimicrobial, antioxidant and in vitro anti-inflammatory activity

of ethanol extract and active phytochemical screening of Wedelia trilobata (L.) Hitchc. Journal of Pharmacognosy and Phytotherapy, 3 (3), 43–51.

Herianto, Kusuma, Z., Nihayati, E. & Prayogo, C. (2018) The plant wisdom of Dayak Ot Danum, Central Kalimantan. The Journal of Tropical Sciences, 8 (2), 130–143. doi:10.11594/jtls.08.02.06.

Hong, L., Zhuo, J., Lei, Q., Zhou, J., Ahmed, S., Wang, C.,Long, Y., Li, F. & Long, C. (2015) Ethnobotany of wild plants used for starting fermented beverages in Shui Communities of Southwest China. Journal of Ethnobiology and Ethnomedicine, 11 (42), 1–21.

doi:10.1186/s13002-015-0028-0.

Kebun Raya Purwodadi (2020) Status tanaman KR Purwodadi, Indonesia: Koleksi tanaman. [Online] Tersedia pada: https://krpurwodadi.lipi.go.id. [Diakses 10 Juni 2020].

Komala, I., Yardi, A., Betha, O.S., Muliati, F. & Ni'mah, M. (2015) Antioxidant and anti-inflammatory activity of the Indonesian ferns, Nephrolepis falcata and Pyrrosia lanceolata. International Journal of

Pharmacy and Pharmaceutical Sciences, 7 (12), 162–165.

Lai, H.Y. & Lim, Y.Y. (2011) Antioxidant properties of some Malaysian ferns. The 3rd International Conference on Chemical, Biological and

Environmental Engineering (IPCBEE). Vol. 20. Singapore, ACSIT Press, pp. 8-12.

Liang, Y.C., Huang, Y.T., Tsai, S.H., Lin-Shiau, S.Y., Chen, C.F. & Lin, J.K. (1999) Suppression of inducible cyclo oxygenase and inducible nitric

oxide synthase by apigenin and related flavonoid in mouse macrophages. Carcinogenesis, 20 (10), 1945–1952. doi:10.1093/carcin/20.10.1945.

Liyaningsih R. & Suyatno (2012) Aktivitas antioksidan senyawa flavanon dari tumbuhan paku Nephrolepis radicans (Burm.) Kuhn. Dalam: Sukarmin, Novita, Rusmini, Yonata, B., Maharani, D.K. & Hidayah, R. (editor) Prosiding Seminar Nasional Kimia

Unesa. Surabaya, 25 Februari 2012. Surabaya, Unesa University Press, hlm. 125-129.

Malan, D.F., Neuba, D.F. & Kouakou, K.L. (2015) Medicinal plants and traditional healing practices in Ehotile people, around the Aby Lagoon (EasternLittoral of Côte d'Ivoire). Journal of Ethnobiology

and Ethnomedicine, 11 (21), 1–18. doi:10.1186/s13002-015-0004-8.

Masal, V.P. (2010) Ethnomedicinal and phytochemical studies of some Pteridophytes of Ratnagiri District from Maharashtra. Master Thesis. Shivaji University.

Mujahid, R., Wahyono, S., Priyambodo, W.J. & Subositi, D. (2019) Studi etnomedicine pengobatan luka terbuka dan sakit kulit pada beberapa etnis di Provinsi Kalimantan Timur. Jurnal Ilmiah Farmasi,

(1), 27–34. doi:10.26874/kjif.v7i1.178.

Newman, D.J., Cragg, G.M. & Snader, K.M. (2000) The influence of natural products upon drug discovery. Natural Product Reports, 17 (2), 175–191. doi: 10.1039/a902202c.

Nugroho, C., Larasati, D., Endah Yuliawati P.S, Ramadhan, N., Sarah, Savira, Sabrina, T.I., Sedayu, A. & Ristanto, R.H. (2018) Karakteristik tumbuhan paku (Pteridophyta) di jalur Ciwalen Taman Nasional Gunung Gede Pangrango, Cisarua, Jawa barat. Biodidaktika: Jurnal Biologi dan Pembelajarannya, 13 (1), 28-37.

Okwu, D.E. (2004) Phytochemicals and vitamin contents of indigenous spices of South Eastern Nigeria. Journal of Sustainable Agricultural Environment, 6, 30–34.

Oloyede, F.A., Fajuke, A.A. & Adeleye, M.O. (2014) Preliminary phytochemical screening of five species of Nephrolepis Swartz in Nigeria. Nigerian Journal of Botany, 27 (2), 153-158.

Pietta, P.G. (2000) Flavonoids as antioxidants. Journal of Natural Products, 63, 1035–1042. doi: 10.1021/np9904509.

Pranowo, D., Noor, E., Haditjaroko, L. & Maddu, A. (2016) Optimasi ekstraksi flavonoid total daun gedi (Abelmoschus manihot L.) dan uji aktivitas antioksidan. Buletin Penelitian Tanaman Rempah

dan Obat, 27 (1), 37–46.

Quattrocchi, U.F.L.S. (2012) CRC world dictionary of medicinal and poisonous plants: Common names, scientific names, eponyms, synonyms, and etymology. Boca Raton, CRC Press.

Rani, D., Khare, P.B. & Dantu, P.K. (2010) In vitro antibacterial and antifungal properties of aqueous and non-aqueous frond extracts of Psilotum nudum, Nephrolepis biserrate, and Nephrolepis cordifolia.

Indian Journal of Pharmaceutical Sciences, 72 (6), 818–822. doi:10.4103/0250-474X.84606.

Renjana, E. & Firdiana, E.R. (2020) Inventarisasi danstrategi penataan koleksi Pteridophyta di rumah kaca Kebun Raya Purwodadi. Bioeksperimen, 6 (2), 89–100.

Riefner, R.E. & Smith, A.R. (2015) Nephrolepis cordifolia (Nephrolepidaceae) naturalized in Southern California (USA): With notes on unintended consequences of escaped garden plants. Journal of the Botanical Research Institute of Texas, 9 (1), 201–212.

Rushing, S. (2006) Tough plants for California Gardens. Beverly, Cool Springs Press. Sajeev, S., Pavithraraj, Adarsh, B.D. & Hedge, S. (2015)

Phytoconstituents of Nephrolepis hirsutula and Pityrogramma calomelanos, two medicinal ferns of The Western Ghats. Indian Fern Journal, 32, 244–256.

Sathiyaraj, G., Muthukumar, T. & Ravindran, K.C. (2015) Ethnomedicinal importance of fern and fern allies traditionally used by tribal people of Palani Hills Kodaikanal,Western Ghats, South India. Journal of Medicinal Herbs and Ethnomedicine, 1 (1), 4–9.

doi:10.5455/jmhe.2015-07-08.

Shah, M.D., Yong, Y.S. & Iqbal, M. (2014) Phytochemical investigation and free radical scavenging activities of essential oil, methanol extract and methanol fractions of Nephrolepis biserrata. International

Journal of Pharmacy and Pharmaceutical Sciences, 6 (9), 269–277.

Shah, N.C. & Singh, S.C. (1990) Hitherto unreported phytotherapeutical uses from tribal pockets of Madhya Padresh, India. Ethnobotany, 2, 91–95.

Singh, S. & Singh, R. (2012) Ethnomedicinal use of pteridophytes in reproductive health of tribal women of Pachmarhi Biosphere Reserve, Madhya Pradesh, India. International Journal of Pharmaceutical Sciences and Research, 3 (12), 4780–4790. doi:10.13040/IJPSR.0975-8232.

Singh, S. & Singh, R. (2013) Utilization of pteridophytes of Achanakmar-Amarkantak Biosphere Reserve, Central India in women’s health and beauty care practices. International Research Journal of Pharmacy, 4 (1), 235–240.

Sistem Informasi Katalog Koleksi Tanaman Kebun Raya Purwodadi (SIKATAN) (2020) Data koleksi tanaman Nephrolepis. [Online] Tersedia pada: https://192.168.82.5/portal/sikatan/data_katalog.

php. [Diakses 28 Mei 2020].

Sodipo, O.A., Akiniyi, J.A. & Ogbunbamosu, J.U. (2000) Studies on certain characteristics of extracts of bark of Pausinystalia johimbe and Pausinystalia macroceras (K.Schum.) Pierre Ex Beille. Global

Journal of Pure Applied and Science, 6 (1), 83–87.

Sureshkumar, J., Silambarasan, R., Bharati, K.A., Krupa, J., Amalraj, S. & Ayyanar, M. (2018) A review on ethnomedicinally important pteridophytes of Indian. Journal of Ethnopharmacology, 219, 269–287. doi:10.1016/j.jep.2018.03.024.

Tewari, D., Samoilă, O., Gocan, D., Mocan, A., Moldovan, C., Devkota, H.P., Atanasov, A.G., Zengin, G., Echeverría, J., Vodnar, D., Szabo, B. & Crişan, G. (2019) Medicinal plants and natural products used

in cataract management. Frontiers in Pharmacology, 10 (466), 1–22. doi:10.3389/fphar.2019.00466.

Trease, G.E. & Evans, W.C. (1999) A textbook of pharmacognosy. 13th Edition. London, Bailliere Tindal Limited. Widowati, W., Herlina, T., Ratnawati, H., Mozef, T. & Immanuel, V. (2011) Potency of antioxidant,

anticholesterol, and platelet antiaggregation ofblack tea (Camelia sinensis). Buletin Penelitian Tanaman Rempah dan Obat, 22 (1), 74–83.

Xu, Z. & Deng, M. (2017) Identification and control of common weeds. Volume 2. Dordrecht, Springer. Yamamoto, Y. & Gaynor, R.B. (2001) Therapeutic potential of inhibition of the NF-kappaB pathway in

the treatment of inflammation and cancer. Journal of Clinical Investigation, 107 (2), 135–142. doi: 10.1172/JCI11914.




DOI: http://dx.doi.org/10.21082/blpn.v27n1.2021.p1-10

Refbacks

  • There are currently no refbacks.




Copyright (c) 2021 Buletin Plasma Nutfah

 


       


Buletin Plasma Nutfah

Jalan Tentara Pelajar 3A, Bogor 16111
Jawa Barat, Indonesia
Phone: (0251) 8339793, 8337975
Call Centre: 08211181677
Fax: (0251) 8338820
E-mail: buletin.plasmanutfah@gmail.com
Website: http://biogen.litbang.pertanian.go.id

ISSN    : 1410-4377
E ISSN : 2549-1393

Accreditation Number200/M/KPT/2020





View My Stats